We link primary sources - including studies, scientific references, and statistics - within each article and also list them in the resources section at the bottom of our articles. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. These tend to appear on areas of the skin that flex or move. People with the condition can develop mild, itchy welts or more severe blisters on the skin. Bullous pemphigoidĪ fault in the immune system causes bullous pemphigoid. It typically causes blisters in the mouth, nose, throat, eyes, or genitals. There are different types of pemphigus, but they all happen when the body’s immune system attacks the healthy cells in the top layer of the skin. People with Hailey-Hailey disease usually experience blisters and irritations on the neck, armpits, and genitals and in the folds of the skin. Hailey-Hailey disease is a rare genetic disorder that causes skin cells to stick together and breaks down the layers of the skin. Specific health conditions that can contribute to the development of intertrigo include: Inverse psoriasisĪlso known as intertriginous psoriasis, this form of psoriasis develops in the folds of the skin. Intertrigo is also more common in adults with incontinence, obesity, diabetes, or a weakened immune system. Most cases occur in hot or humid environments and during the summer. In babies, it is often called diaper rash. While it can happen at any age, intertrigo tends to affect infants, older people, and those with a reduced ability to move around. The warm, damp environment makes the skin conducive to irritation and the growth of yeast and bacteria, which can lead to an infection. Areas of moist skin rubbing together cause intertrigo.
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